iCo Therapeutics iCo-007 Results to be Presented at Prestigious Ocular Conference
February 19, 2009
VANCOUVER, Canada— iCo Therapeutics Inc. (TSX-V: ICO) is pleased to announce that early results for iCo’s Diabetic Macular Edema (DME) candidate, iCo-007, will be highlighted in a presentation at a prominent ocular conference.
The presentation will be given by Geeta A. Lalwani, MD, Assistant Professor of Clinical Ophthalmology, Vitreoretinal Diseases and Surgery at the Bascom Palmer Eye Institute University of Miami Miller School of Medicine. The Bascom Palmer Eye Institute is one of the premier eye centres in the world, and one of the four U.S. sites conducting iCo’s ongoing iCo-007 clinical trial. Along with Philip Rosenfeld, MD, Dr. Lalwani is an investigator participating in the Phase I clinical trial in DME patients. The primary endpoint of the open label, dose escalating trial is safety, with visual acuity and measures of retinal thickness serving as secondary endpoints.
The conference, “Angiogenesis, Exudation and Degeneration 2009”, will be held on Saturday, February 21, 2009 at the Ritz-Carlton Key Biscayne. The conference will feature prominent scientists, clinicians and healthcare experts in neovascular diseases of the eye, including AMD and DME. Dr. Lalwani’s presentation will be held at 4:25pm.
About iCo-007
iCo-007 is expected to decrease swelling in the retina and related visual impairment by decreasing the signaling of multiple growth factors, including VEGF, IGF, bFGF, EPO and HGF that signal through the c-Raf kinase / MAP kinase pathway. iCo-007 may also be a potential treatment for certain oncology indications, as c-Raf kinase is the predominant Raf isoform responsible for regulating cellular growth in ovarian cancer. iCo-007 is an antisense drug discovered by Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) and licensed to iCo Therapeutics for the treatment of various eye diseases.
